Research & News

Research & news

Curated coverage of new papers, first-in-human reports and technique developments in interventional CT/MRI-guided (and adjacent) therapy — populated automatically from each monthly newsletter's own research. Showing the last 12 months; see Older Research & News for everything before that.

Clinical Criteria for Improved Outcomes in Patients Who Undergo Percutaneous CT-Guided Pudendal Nerve Cryoablation: A Retrospective Analysis.

Journal of vascular and interventional radiology : JVIR · 2026 Sep

A 10-year retrospective analysis of 362 CT-guided pudendal nerve cryoablations found that predefined clinical selection criteria (antecedent event, unilateral pudendal-distribution pain) were associated with improved outcomes among the 75 unilateral cases with adequate follow-up.

https://pubmed.ncbi.nlm.nih.gov/42276242/

CT-guided RFA using a urine-hyperexcreting protocol in treating endophytic RCC: long-term outcomes in a single-arm study.

The British journal of radiology · 2026 Sep 1

A single-arm study of 61 patients undergoing CT-guided RFA of endophytic RCC using a urine-hyperexcreting protocol (furosemide plus saline) reported a 5-year local tumor progression-free survival rate of 96.7% with long-term follow-up (median 54 months).

https://pubmed.ncbi.nlm.nih.gov/42500987/

Comparison of automated robotic arm-assisted PET/computed tomography-guided metabolic bone marrow biopsy with conventional bone marrow trephine biopsy for evaluating bone marrow infiltration in newly diagnosed lymphoma.

Nuclear medicine communications · 2026 Sep 1

In a prospective study of 169 treatment-naive lymphoma patients, automated robotic-arm-assisted PET/CT-guided bone marrow biopsy was compared with conventional trephine biopsy in 44 patients with focal FDG-avid lesions to evaluate diagnostic performance for bone marrow infiltration.

https://pubmed.ncbi.nlm.nih.gov/42087722/

Interleaved Imaging and Actuation for Real-Time MRI During Active Control of a Magnetically-Actuated Robotic Catheter.

IEEE transactions on bio-medical engineering · 2026 Sep

Researchers developed an interleaved imaging-actuation method that synchronizes magnetically-actuated robotic catheter control with MR image acquisition, showing no statistically significant increase in image artifacts compared to the catheter at rest while maintaining trajectory tracking accuracy.

https://pubmed.ncbi.nlm.nih.gov/41370149/

Saline tract sealing to prevent pneumothorax and chest tube placement after computed tomography (CT)-guided lung biopsy: a systematic review and meta-analysis.

Clinical radiology · 2026 Sep

A systematic review and meta-analysis assessed saline tract-sealing techniques (versus autologous blood, fibrin glue, collagen plugs) to reduce pneumothorax after CT-guided lung biopsy, noting baseline pneumothorax rates of about 25% and chest tube requirement in 5-6% of cases.

https://pubmed.ncbi.nlm.nih.gov/42480290/

Tract Embolization versus No Embolization after CT-Guided Lung Biopsy: A Systematic Review and Meta-Analysis.

Journal of vascular and interventional radiology : JVIR · 2026 Sep

A systematic review and meta-analysis compared tract embolization versus no embolization after CT-guided percutaneous lung biopsy, pooling risk ratios across studies to assess effectiveness in preventing pneumothorax and chest tube placement.

https://pubmed.ncbi.nlm.nih.gov/42142830/

Iceball Margin < 5 mm Is Associated with Local Failure after CT-Guided Cryoablation of cT1a Renal Cell Carcinoma.

Journal of vascular and interventional radiology : JVIR · 2026 Sep

In a study of CT-guided percutaneous cryoablation for cT1a renal cell carcinoma, an iceball minimal treatment margin under 5 mm was associated with local treatment failure, based on matched-control analysis of intraprocedural and planning CT data.

https://pubmed.ncbi.nlm.nih.gov/42288248/

MRI-guided endovascular robotics: A roadmap to MRI-native systems.

APL bioengineering · 2026 Sep

A perspective outlines the roadmap toward MRI-native endovascular robotic systems, arguing that translating MRI-guided robotic catheter interventions into routine practice requires MRI-robot co-design rather than simple compatibility adaptation of instruments, imaging/feedback, and navigation.

https://pubmed.ncbi.nlm.nih.gov/42428809/

Robot-assisted biopsy a bibliometric analysis of global trends, hotspots, and emerging frontiers (2000-2025).

Journal of robotic surgery · 2026 Aug 28

A bibliometric analysis of global research from 2000-2025 maps trends, key contributors, and emerging frontiers in robot-assisted biopsy techniques, which combine robotic manipulation, path planning, and multimodal imaging fusion for precise sampling of deep-seated lesions across urology, neurosurgery, and thoracic intervention.

https://pubmed.ncbi.nlm.nih.gov/42663785/

Do robotic needle systems improve precision and efficiency? Evidence from a systematic review and meta-analysis of clinical and preclinical studies

Journal of Robotic Surgery · 2026-08-14

Pooling 40 studies (14 clinical, 834 patients), robotic needle guidance modestly improved placement accuracy but showed no statistically significant advantage in procedure time, success rate, or complications versus manual technique - a useful check on the assumption that robotic automatically means better outcomes.

https://pubmed.ncbi.nlm.nih.gov/42599611/

Ion Robotic Bronchoscopy-Guided Microwave Ablation Under Augmented Fluoroscopy: An Initial Case Series and Comparative Procedural Workflow Analysis

Cardiovascular and Interventional Radiology · 2026-08-13

In a 21-patient prospective cohort, Ion robotic-bronchoscopy-guided microwave ablation of lung lesions matched or beat a historical electromagnetic-navigation cohort on technical success (100% vs 92.9%) while cutting navigation time from 28.5 to 2 minutes and radiation dose nearly in half.

https://pubmed.ncbi.nlm.nih.gov/42595799/

Flexible intervention workflow for MRI guided robotic prostate seed brachytherapy

Journal of Applied Clinical Medical Physics · 2026-08

A phantom study (not yet clinical) repurposing an existing MRI-compatible robotic biopsy guide for seed brachytherapy achieved sub-millimeter robotic targeting precision, though seed-release and MRI-only localization errors still measurably affected dose coverage.

https://pubmed.ncbi.nlm.nih.gov/42605022/

Efficacy of saline tract sealing after CT-Guided lung biopsy: a systematic review and meta-analysis

Clinical Radiology · 2026-08

Pooling 7 studies (1,455 patients), sealing the needle tract with saline after CT-guided lung biopsy roughly halved the rate of pneumothorax and cut chest-tube placement by about 75% versus usual care.

https://pubmed.ncbi.nlm.nih.gov/42322811/

Robotic-Assisted Computed Tomography-Guided Percutaneous Bone Procedures: A Prospective Multicenter Pilot Study

Cardiovascular and Interventional Radiology · 2026-07-29

A prospective multicenter pilot (34 patients, 90 needle insertions for spine/pelvis bone consolidation or ablation, using the Epione platform) found robotic insertion feasible in 98.9% of cases with sub-3mm targeting accuracy and no device-related adverse events. Disclosed conflict of interest: the study was institutionally funded by Quantum Surgical, the platform's manufacturer.

https://pubmed.ncbi.nlm.nih.gov/42527616/

First-in-human pilot study of a robotic-assisted system for image-guided trans-thoracic lung biopsy: Clinical feasibility and exploratory post-hoc AI trajectory analysis

European Journal of Radiology · 2026-07-16

In 30 evaluable patients, a patient-mounted robotic needle-guidance platform (ANT-C) achieved 100% clinical success, with procedure time roughly halving (61 to 31 minutes) as operators gained experience.

https://pubmed.ncbi.nlm.nih.gov/42492116/

Paramaxillary (Transfacial) Approach for CT-Guided Head and Neck Biopsies

AJNR · 2026-07-01

A technique paper detailing a CT-guided transfacial pathway for biopsying deep head-and-neck lesions (parapharyngeal space, carotid space, skull base) that are otherwise hard to reach safely.

https://pubmed.ncbi.nlm.nih.gov/42014171/

Analgosedation in interventional radiology

RoFo · 2026-06-17

A CIRSE-linked position paper argues interventional radiologists should build their own formal, guideline-backed sedation/analgesia competency rather than relying on anesthesiology capacity, citing CT-guided brachytherapy and percutaneous tumor ablation as procedures where non-anesthesiologist-administered sedation is already shown safe.

https://pubmed.ncbi.nlm.nih.gov/42309123/

Computed tomography-guided vs conventional catheter ablation for ventricular tachycardia: the InEurHeart trial

European Heart Journal · 2026-06-16

A 14-center randomized trial (n=113) found CT-guided ventricular tachycardia ablation cut procedure time by 19-28% versus conventional ablation, with comparable safety and a non-significant trend toward better 1-year VT-free survival (76.8% vs 67.3%).

https://pubmed.ncbi.nlm.nih.gov/41667137/

Micro-ultrasound guided versus multiparametric MRI-guided prostate biopsy: a systematic review and meta-analysis

International Urology and Nephrology · 2026-06-15

Across 12 studies (4,318 patients), micro-ultrasound-guided biopsy detected clinically significant prostate cancer at rates statistically indistinguishable from MRI-guided biopsy - a cheaper, more available modality performing comparably.

https://pubmed.ncbi.nlm.nih.gov/42295630/

MRI-guided adaptive radiotherapy for high grade glioma (UNITED): a single-centre, single-arm, non-inferiority, phase 2 trial

The Lancet Oncology · 2026-06

A phase 2 trial (n=98) of small-margin, MRI-guided adaptive radiotherapy for glioblastoma on a 1.5T MR-Linac found only a 4% marginal-failure rate, supporting margin de-escalation without an apparent safety cost.

https://pubmed.ncbi.nlm.nih.gov/42134380/